Resources: Naloxone

Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Resource Center

Provides training and technical assistance to jurisdictions to develop, implement, and expand comprehensive efforts to identify, respond to, treat, and support individuals impacted by the use and misuse of opioids, stimulants, and other substances. Promotes access to treatment and recovery services in the criminal justice system, data collection and sharing, leveraging resources and funding, and efforts to prevent substance misuse.

Resource Type: Training
Sponsor: Bureau of Justice Assistance (BJA)
Connecting Communities to Substance Use Services: Practical Approaches for First Responders

Provides information to first responder agencies, communities, and other stakeholders to support practices and approaches for first responders to connect people to substance use treatment and other support services. Offers evidence-based strategies, public health approaches, resources, and program models, including best practices for responding to opioid overdoses. Considers potential challenges, such as those faced in rural areas, and other factors when implementing initiatives to support people who use drugs.

Resource Type: Document / Report
Date: 08/2023
Sponsor: Substance Abuse and Mental Health Services Administration (SAMHSA)
Fentanyl and Carfentanil

Describes the uses and dangers of fentanyl and carfentanil, which are both extremely potent synthetic opioids. Includes methods for reducing opioid use and overdoses, including medication-assisted treatment (MAT) and naloxone distribution.

Resource Type: Document / Report
Date: 01/2018
Sponsor: VA Pharmacy Benefits Management (PBM) Services
Law Enforcement Naloxone Toolkit

Serves as a clearinghouse of resources to assist law enforcement agencies across the country in establishing a naloxone program to reduce the harm and number of deaths associated with opioid overdose. Offers information on a range of topics related to operating a naloxone program, including naloxone medication and its role in law enforcement; acquiring and administering naloxone; training law enforcement; liability and risk issues; and collaboration with other agencies and stakeholders. Provides a variety of tools and materials, such as sample documents and templates for data collection forms, training materials, press releases, community outreach materials, and more. Product of the Bureau of Justice Assistance's (BJA) National Training and Technical Assistance Center (NTTAC) funded by a contract through the U.S. Department of Justice (DOJ) Office of Justice Programs (OJP).

Resource Type: Website
Sponsor: Bureau of Justice Assistance (BJA)
Lessons Learned from the Rural Opioid Overdose Reversal Program

Documents the challenges, successes, and lessons learned from the Rural Opioid Overdose Reversal Program (ROOR), a 2015 pilot grant program administered by the Health Resources and Services Administration's (HRSA) Federal Office of Rural Health Policy. Includes resources to support related projects and programs, with links to training, data strategies, and outreach tools.

Resource Type: Website
Date: 04/2017
Sponsor: Federal Office of Rural Health Policy (FORHP)
Medicaid Coverage of Medications to Reverse Opioid Overdose and Treat Alcohol and Opioid Use Disorder

Provides information on the availability of, and access to, medications for treating alcohol use disorder (AUD) and opioid use disorder (OUD), and for reversing opioid overdoses within state Medicaid plans. Discusses policies and regulations affecting access to these medications and reviews the present coverage and availability of the medications to Medicaid beneficiaries in each state. Includes 5 innovative models for expanding medication access to underserved Medicaid populations, including those residing in rural areas, American Indian/Alaska Native communities, and individuals recently released from incarceration.

Resource Type: Document / Report
Date: 01/2024
Sponsor: Substance Abuse and Mental Health Services Administration (SAMHSA)
Nonfatal Drug Overdose Surveillance Dashboard

Interactive map providing data on suspected nonfatal drug overdoses in pre-hospital care settings in the U.S. at the national, state, and county level. Offers data on nonfatal drug overdose incidence and trends, including overdose rates, number/rate of naloxone administration, and average emergency medical services (EMS) response time. Allows users to explore disparities according to demographic characteristics, such as age, race, gender, and frontier, rural, and urban geographies, as well as by the suspected drug involved.

Resource Type: Map / Chart
Date: 2023
Sponsor: Office of National Drug Control Policy (ONDCP)
Opioid Overdose Education & Naloxone Distribution (OEND)

Provides an overview of the U.S. Department of Veterans Affairs (VA) Opioid Overdose Education & Naloxone Distribution (OEND) program. Focuses on reducing opioid overdoses and deaths among veterans through education and training for prevention, recognition, rescue response, and naloxone kit use. Includes OEND videos and materials for providers and patients.

Resource Type: Website
Sponsor: VA Pharmacy Benefits Management (PBM) Services
Opioid Safety Initiative Toolkit

Toolkit sharing field guidance, resources, and presentations to support clinical decisions about starting, continuing, or tapering opioid therapy, and other challenges related to safe opioid prescribing. Includes patient and provider education, clinical tools, and other resources.

Resource Type: Website
Sponsor: Veterans Health Administration (VHA)
Opioid Use Disorder: Rural Policy Brief

Provides a brief overview of the issue of opioid overdoses in rural areas and offers public health policy and strategy options to help communities prevent and reduce rural opioid overdose deaths. Includes case studies describing interventions implemented in 3 states.

Resource Type: Website
Sponsor: Centers for Disease Control and Prevention (CDC)
Opioid-Overdose Reduction Continuum of Care Approach: A Guide for Policymakers for Implementing Evidence-Based Strategies That Address Opioid Overdose

Provides guidance to policymakers, communities, and key stakeholders to develop and implement system- and practice-level changes to reduce opioid overdose deaths. Presents results from the National Institutes of Health (NIH) Helping to End Addiction Long-term (HEAL) Initiative's HEALing Communities Study. Outlines priority populations and 19 evidence-based interventions to prevent and reduce opioid related overdose deaths. Offers resources on various topics related to opioid overdose and highlights model programs, including those serving rural areas.

Resource Type: Document / Report
Date: 2023
Sponsors: National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH)
Overdose Prevention Strategy

Details the U.S. Department of Health and Human Services strategy to respond to drug overdoses and prevent overdose deaths across the U.S. Shares research, resources, and evidence-informed overdose interventions focused on 4 priority areas: primary prevention, harm reduction, evidence-based treatment, and recovery support. Offers strategies and resources designed to increase coordination among key stakeholders, reduce stigma, and expand access to healthcare and treatment for underserved populations, including rural and tribal communities.

Resource Type: Website
Sponsor: U.S. Department of Health & Human Services
SAMHSA Medications for Substance Use Disorders

Provides an overview of medications for opioid use disorder (MOUD) and medications for alcohol use disorder (MAUD), as well as information on opioid treatment programs (OTPs). Describes current federal regulations and requirements for practitioners to prescribe MOUD. Includes information and training resources for healthcare providers, researchers, and patients.

Resource Type: Website
Sponsor: Substance Abuse and Mental Health Services Administration (SAMHSA)
SAMHSA Opioid Overdose Reversal Medications (OORM)

Describes how naloxone and nalmefene are used and the side effects of opioid overdose reversal medications (OORMs). Briefly discusses causes of opioid overdose. Highlights how the Substance Abuse and Mental Health Services Administration (SAMHSA) is working with communities, local governments, local law enforcement, and state and federal partners to expand naloxone/nalmefene use.

Resource Type: Website
Sponsor: Substance Abuse and Mental Health Services Administration (SAMHSA)
Specifying Monitoring and Evaluation Measures for Local Overdose Prevention and Response Strategies: A Toolkit

Provides information and resources for local health departments and community organizations implementing or expanding overdose prevention and response strategies at the local level. Offers guidance in developing practical measurement strategies to monitor progress, demonstrate accountability, and assess the outcomes and impact of grant-funded overdose initiatives. Includes examples from programs implemented in rural counties.

Resource Type: Document / Report
Date: 2024
Sponsor: Centers for Disease Control and Prevention (CDC)
University of Rhode Island (URI) Community First Responder Program ROTA-R

Serves as a Rural Opioid Technical Assistance Regional Center (ROTA-R) in New England. Provides support, technical assistance, and naloxone training to address substance use disorder (SUD) and overdose throughout rural areas in Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont.

Resource Type: Training
Sponsor: Substance Abuse and Mental Health Services Administration (SAMHSA)
VA PBM: Academic Detailing Services (ADS) - Educational Materials

Provides access to education materials developed by the VA Pharmacy Benefits Management Services (PBM) Academic Detailing Services (ADS) sharing evidence-based treatments to help providers improve the health of veterans. Offers provider and patient education tools and outreach resources to encourage evidence-based decision making for a variety of medical conditions and diseases, including opioid use disorder (OUD) and substance use disorder (SUD), pain, harm reduction, suicide, dementia, depression, HIV, post-traumatic stress disorder (PTSD), and more.

Resource Type: Website
Sponsor: VA Pharmacy Benefits Management (PBM) Services